Platform

The platform for the genome of the species.

Pipeline v7 · 22 analyzers · 6 polygenic methods

The flywheel · your Mirror over time

ENCRYPTED · YOURSMirroryour digital twin⟲ OPTIMIZINGAI LAYERreasoning · voice · memoryTHE PERSONyou · physicalGenotyperaw DNA · any formatPhenotypelabs · wearables · bodyExtended phenotypebehaviour · environmentEXCHANGE · A FLOW OF DATAaspects couple to other MirrorsThe network of Mirrors is HaeckelONE · LINEAGE · THE SPECIESHAECKEL'S OUTPUT RETURNS TO YOUyou act · your biology improvesVALUE RETURNS
01You
02Mirror
03Return
04Couple
05Species
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The system · what the platform is made of

IngestDNA · any format23andMe · VCF · FASTQHarmonizebuild · strand · liftoverpipeline v7THE ENGINE22 analyzers6 polygenic methodsDBKG · PGx-gatedTHE TWINMirrordigital twin · 3 layersTHE SURFACESMirrorOptimizeLabNetworksOriginsGenomeTHE NETWORK · CONSENT-NATIVEpaid accessfollowprivateINDIVIDUAL · LINEAGE · SPECIESTHE HERU SUBSTRATEthe moat: reference data + calibrationLD panels · 5 populationsgnomAD · HGDP + TGPPGS CatalogGRCh37 / 38 referencesCalibration corpus
01Ingest
02Engine
03Twin
04Surfaces
05Substrate
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At scale

One instrument, every resolution.

Most genomics ends at a report. Haeckel is where the genome lives and keeps working: one encrypted, queryable platform that holds the genotype, phenotype, and extended phenotype, instruments a genome once, then optimizes, simulates, and interrogates it for as long as it exists. The same instrument operates at three resolutions, from one person to the species.

The model

Three layers, one digital twin

Each individual is a computational replica of their biology across three layers.

Genotype

The genome. Variants, raw and harmonized DNA from any provider or whole-genome source.

Phenotype

The expressed biology. Health, traits, biomarkers, wearables, hormones, cognition, body composition.

Extended phenotype

What the genes produce beyond the body. Lineage, offspring, behavior, environment, footprint.

The stack

Five operations on the twin

The platform is five operations, in order. Each is a layer of one instrument.

DigitalizeInstrument

Ingest DNA in any format, harmonize it, and normalize the three layers into one encrypted, queryable twin.

OptimizeDecision intelligence

Multi-objective optimization of the phenotype against the genome, gated for drug-gene safety.

SimulateIn-silico modeling

Counterfactual and generative modeling: offspring, embryos, interventions, lineages.

InteractThe agent

Natural-language query over the twin, and across the population, in every conceivable way.

ExchangeConsented marketplace

Individuals own their twin and control access to it. The data stays on the platform; only interaction is shared.

Resolution

Individual. Lineage. Species.

The value is not linear. It compounds as the shared space fills, because cross-lineage and population optimization only unlock at scale.

IndividualResolve one genome across every layer
LineageInheritance, and the generations forward and back
SpeciesThe aggregate: optimization across a meaningful share of humanity
Data flow

From a raw file to a living model

Five stages, each independently tested and versioned.

IngestionAny format · 23andMe · AncestryDNA · VCF · FASTQ
HarmonizationBuild detection · strand · liftover
22 AnalyzersAncestry, health, traits, pharma, lineage
PRS Engine6 polygenic methods + ensemble
MirrorThe conversational interface
Modules

22 analyzers, every layer

Each module sits under one tab bar, every one with a named, peer-reviewed method behind it.

Ancestry v4.0
MLE-EM + spatial thinning + Bootstrap Wald + AMR deconvolution
Health
89-gene penetrance modeling, sex-aware X-linked
Traits
Genotype-to-phenotype across monogenic and polygenic traits
Haplogroup v2.1
Recursive phylogenetic traversal, back-mutations, RC fallback
APOE
Four-tier resolution across chip versions
HLA
Imputation and typing of the MHC region
PCA
Principal-component projection onto reference cohorts
Archaic
Neanderthal & Denisovan via S*, ABBA-BABA D-stats, HMM
ROH
Runs of homozygosity, consanguinity inference
HIrisPlex
Eye / hair / skin prediction, coverage-gated
Pharmacogenomics
CPIC star-allele calling, 10 FDA Black Box alerts
Nutrigenomics
Diet-relevant variant interpretation
Kinship
KING-robust relationship inference
Data Quality
Coverage, call rate, and build integrity gates
Runtime
Next.js 14 · Vercel
Database
Neon Postgres + pgvector
1536-dimensional embeddings
File storage
Cloudflare R2
Encrypted at rest
Reference panels
1000 Genomes + HGDP
60+ populations · 5 LD reference panels